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Human Lipocalin-Type Prostaglandin D Synthase-Based Drug Delivery System for Poorly Water-Soluble Anti-Cancer Drug SN-38

Lipocalin-type prostaglandin D synthase (L-PGDS) is a member of the lipocalin superfamily, which is composed of secretory transporter proteins, and binds a wide variety of small hydrophobic molecules. Using this function, we have reported the feasibility of using L-PGDS as a novel drug delivery vehi...

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Detalles Bibliográficos
Autores principales: Nakatsuji, Masatoshi, Inoue, Haruka, Kohno, Masaki, Saito, Mayu, Tsuge, Syogo, Shimizu, Shota, Ishida, Atsuko, Ishibashi, Osamu, Inui, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631600/
https://www.ncbi.nlm.nih.gov/pubmed/26529243
http://dx.doi.org/10.1371/journal.pone.0142206