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The utility of cardiac magnetic resonance imaging in Kounis syndrome

INTRODUCTION: Current diagnostic measurements used to assess myocardial involvement in Kounis syndrome, such as electrocardiography (ECG), cardiac enzymes, and troponin levels, are relatively insensitive to small but potentially significant functional change. According to our review of the literatur...

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Autores principales: Okur, Aylin, Kantarci, Mecit, Karaca, Leyla, Ogul, Hayri, Aköz, Ayhan, Kızrak, Yesim, Aslan, Sahin, Pirimoglu, Berhan, Aksakal, Enbiya, Emet, Mucahit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631737/
https://www.ncbi.nlm.nih.gov/pubmed/26677363
http://dx.doi.org/10.5114/pwki.2015.54017
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author Okur, Aylin
Kantarci, Mecit
Karaca, Leyla
Ogul, Hayri
Aköz, Ayhan
Kızrak, Yesim
Aslan, Sahin
Pirimoglu, Berhan
Aksakal, Enbiya
Emet, Mucahit
author_facet Okur, Aylin
Kantarci, Mecit
Karaca, Leyla
Ogul, Hayri
Aköz, Ayhan
Kızrak, Yesim
Aslan, Sahin
Pirimoglu, Berhan
Aksakal, Enbiya
Emet, Mucahit
author_sort Okur, Aylin
collection PubMed
description INTRODUCTION: Current diagnostic measurements used to assess myocardial involvement in Kounis syndrome, such as electrocardiography (ECG), cardiac enzymes, and troponin levels, are relatively insensitive to small but potentially significant functional change. According to our review of the literature, there has been no study using magnetic resonance imaging (MRI) on Kounis syndrome except for one case report. AIM: To identify the findings of dynamic contrast-enhanced magnetic resonance imaging (CE-MRI) in patients with Kounis syndrome (KS) type 1. MATERIAL AND METHODS: We studied 26 patients (35 ±11.5 years, 53.8% male) with known or suspected KS type 1. The patients underwent precontrast, first-pass, and delayed enhancement cardiac MRI (DE-MRI). Contrast enhancement patterns, edema, hypokinesia, and localization for myocardial lesions were evaluated in all KS type 1 patients. RESULTS: Contrast-enhanced magnetic resonance imaging demonstrated an early-phase subendocardial contrast defect, and T2-weighted images showed high-signal intensity consistent with edema in lesion areas. None of the lesion areas was found upon contrast enhancement on DE-MRI. The area of early-phase subendocardial contrast defect was reported as follows: the interventricular septum in 14 (53.8%) patients, the left ventricular lateral wall in 8 (30.7%), and the left ventricular apex in 4 (15.4%). CONCLUSIONS: Dynamic cardiac MR imaging is a reliable tool for assessing cardiac involvement in Kounis syndrome. Delayed contrast-enhanced images show normal washout in the subendocardial lesion area in patients with Kounis syndrome type 1.
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spelling pubmed-46317372015-12-16 The utility of cardiac magnetic resonance imaging in Kounis syndrome Okur, Aylin Kantarci, Mecit Karaca, Leyla Ogul, Hayri Aköz, Ayhan Kızrak, Yesim Aslan, Sahin Pirimoglu, Berhan Aksakal, Enbiya Emet, Mucahit Postepy Kardiol Interwencyjnej Original Paper INTRODUCTION: Current diagnostic measurements used to assess myocardial involvement in Kounis syndrome, such as electrocardiography (ECG), cardiac enzymes, and troponin levels, are relatively insensitive to small but potentially significant functional change. According to our review of the literature, there has been no study using magnetic resonance imaging (MRI) on Kounis syndrome except for one case report. AIM: To identify the findings of dynamic contrast-enhanced magnetic resonance imaging (CE-MRI) in patients with Kounis syndrome (KS) type 1. MATERIAL AND METHODS: We studied 26 patients (35 ±11.5 years, 53.8% male) with known or suspected KS type 1. The patients underwent precontrast, first-pass, and delayed enhancement cardiac MRI (DE-MRI). Contrast enhancement patterns, edema, hypokinesia, and localization for myocardial lesions were evaluated in all KS type 1 patients. RESULTS: Contrast-enhanced magnetic resonance imaging demonstrated an early-phase subendocardial contrast defect, and T2-weighted images showed high-signal intensity consistent with edema in lesion areas. None of the lesion areas was found upon contrast enhancement on DE-MRI. The area of early-phase subendocardial contrast defect was reported as follows: the interventricular septum in 14 (53.8%) patients, the left ventricular lateral wall in 8 (30.7%), and the left ventricular apex in 4 (15.4%). CONCLUSIONS: Dynamic cardiac MR imaging is a reliable tool for assessing cardiac involvement in Kounis syndrome. Delayed contrast-enhanced images show normal washout in the subendocardial lesion area in patients with Kounis syndrome type 1. Termedia Publishing House 2015-09-28 2015 /pmc/articles/PMC4631737/ /pubmed/26677363 http://dx.doi.org/10.5114/pwki.2015.54017 Text en Copyright © 2015 Termedia http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Okur, Aylin
Kantarci, Mecit
Karaca, Leyla
Ogul, Hayri
Aköz, Ayhan
Kızrak, Yesim
Aslan, Sahin
Pirimoglu, Berhan
Aksakal, Enbiya
Emet, Mucahit
The utility of cardiac magnetic resonance imaging in Kounis syndrome
title The utility of cardiac magnetic resonance imaging in Kounis syndrome
title_full The utility of cardiac magnetic resonance imaging in Kounis syndrome
title_fullStr The utility of cardiac magnetic resonance imaging in Kounis syndrome
title_full_unstemmed The utility of cardiac magnetic resonance imaging in Kounis syndrome
title_short The utility of cardiac magnetic resonance imaging in Kounis syndrome
title_sort utility of cardiac magnetic resonance imaging in kounis syndrome
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631737/
https://www.ncbi.nlm.nih.gov/pubmed/26677363
http://dx.doi.org/10.5114/pwki.2015.54017
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