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Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis

Next-generation sequencing (NGS) has been used to investigate the diversity and maturation of broadly neutralizing antibodies (bNAbs) in HIV-1-infected individuals. However, the application of NGS to the preclinical assessment of human vaccines, particularly the monitoring of vaccine-induced B-cell...

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Detalles Bibliográficos
Autores principales: Dai, Kaifan, He, Linling, Khan, Salar N., O’Dell, Sijy, McKee, Krisha, Tran, Karen, Li, Yuxing, Sundling, Christopher, Morris, Charles D., Mascola, John R., Hedestam, Gunilla B. Karlsson, Wyatt, Richard T., Zhu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631801/
https://www.ncbi.nlm.nih.gov/pubmed/26530382
http://dx.doi.org/10.1128/mBio.01375-15

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