Cargando…
Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis
Next-generation sequencing (NGS) has been used to investigate the diversity and maturation of broadly neutralizing antibodies (bNAbs) in HIV-1-infected individuals. However, the application of NGS to the preclinical assessment of human vaccines, particularly the monitoring of vaccine-induced B-cell...
Autores principales: | Dai, Kaifan, He, Linling, Khan, Salar N., O’Dell, Sijy, McKee, Krisha, Tran, Karen, Li, Yuxing, Sundling, Christopher, Morris, Charles D., Mascola, John R., Hedestam, Gunilla B. Karlsson, Wyatt, Richard T., Zhu, Jiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631801/ https://www.ncbi.nlm.nih.gov/pubmed/26530382 http://dx.doi.org/10.1128/mBio.01375-15 |
Ejemplares similares
-
OA05-05. Impact of in vivo CD4 binding during HIV-1 Env trimer immunizations of rhesus macaques
por: Douagi, I, et al.
Publicado: (2009) -
HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation
por: Dai, Kaifan, et al.
Publicado: (2016) -
Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation
por: Martinez, Paola, et al.
Publicado: (2015) -
Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
por: Sundling, Christopher, et al.
Publicado: (2010) -
Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
por: Sundling, Christopher, et al.
Publicado: (2010)