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EtpE Binding to DNase X Induces Ehrlichial Entry via CD147 and hnRNP-K Recruitment, Followed by Mobilization of N-WASP and Actin

Obligate intracellular bacteria, such as Ehrlichia chaffeensis, perish unless they can enter eukaryotic cells. E. chaffeensis is the etiological agent of human monocytic ehrlichiosis, an emerging infectious disease. To infect cells, Ehrlichia uses the C terminus of the outer membrane invasin entry-t...

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Detalles Bibliográficos
Autores principales: Mohan Kumar, Dipu, Lin, Mingqun, Xiong, Qingming, Webber, Mathew James, Kural, Comert, Rikihisa, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631803/
https://www.ncbi.nlm.nih.gov/pubmed/26530384
http://dx.doi.org/10.1128/mBio.01541-15