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Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

Linezolid is an oxazolidinone with potent activity against Mycobacterium tuberculosis. Linezolid toxicity in patients correlates with the dose and duration of therapy. These toxicities are attributable to the inhibition of mitochondrial protein synthesis. Clinically relevant linezolid regimens were...

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Detalles Bibliográficos
Autores principales:	Brown, Ashley N., Drusano, George L., Adams, Jonathan R., Rodriquez, Jaime L., Jambunathan, Kalyani, Baluya, Dodge L., Brown, David L., Kwara, Awewura, Mirsalis, Jon C., Hafner, Richard, Louie, Arnold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631805/ https://www.ncbi.nlm.nih.gov/pubmed/26530386 http://dx.doi.org/10.1128/mBio.01741-15

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