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Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease

We present an 18-year-old, immunocompetent Austrian military conscript with cervical lymphadenopathy, fever, back-pain, and persistent inflammation markers despite two weeks of antimicrobial therapy with ampicillin/sulbactam. All specific laboratory investigations for identification of a specific et...

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Autores principales: Knafl, D., Lötsch, F., Burgmann, H., Goliasch, G., Poeppl, W., Ramharter, M., Thalhammer, F., Schuster, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631868/
https://www.ncbi.nlm.nih.gov/pubmed/26576306
http://dx.doi.org/10.1155/2015/317260
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author Knafl, D.
Lötsch, F.
Burgmann, H.
Goliasch, G.
Poeppl, W.
Ramharter, M.
Thalhammer, F.
Schuster, C.
author_facet Knafl, D.
Lötsch, F.
Burgmann, H.
Goliasch, G.
Poeppl, W.
Ramharter, M.
Thalhammer, F.
Schuster, C.
author_sort Knafl, D.
collection PubMed
description We present an 18-year-old, immunocompetent Austrian military conscript with cervical lymphadenopathy, fever, back-pain, and persistent inflammation markers despite two weeks of antimicrobial therapy with ampicillin/sulbactam. All specific laboratory investigations for identification of a specific etiology, including blood cultures and autoantibodies, were inconspicuous. Abdominal computed tomography showed multiple hypodense hepatosplenic lesions and osteomyelitis of the thoracic and lumbar spine with base plate fracture. Based on the patient's history, clinical presentation, and radiological findings, serology for cat scratch disease (CSD) was performed and high B. henselae specific IgM and IgG antibodies were detected. Due to its variety of clinical presentations, diagnosis of CSD is challenging, especially in the absence of a history of specific exposure. This case report shall remind the physician that cat scratch disease is a common disease, mainly presenting with fever and lymphadenopathy in young patients. Nevertheless CSD has many different and rare forms of presentations, including hepatosplenic lesions and bone involvement as shown in this case.
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spelling pubmed-46318682015-11-16 Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease Knafl, D. Lötsch, F. Burgmann, H. Goliasch, G. Poeppl, W. Ramharter, M. Thalhammer, F. Schuster, C. Case Rep Infect Dis Case Report We present an 18-year-old, immunocompetent Austrian military conscript with cervical lymphadenopathy, fever, back-pain, and persistent inflammation markers despite two weeks of antimicrobial therapy with ampicillin/sulbactam. All specific laboratory investigations for identification of a specific etiology, including blood cultures and autoantibodies, were inconspicuous. Abdominal computed tomography showed multiple hypodense hepatosplenic lesions and osteomyelitis of the thoracic and lumbar spine with base plate fracture. Based on the patient's history, clinical presentation, and radiological findings, serology for cat scratch disease (CSD) was performed and high B. henselae specific IgM and IgG antibodies were detected. Due to its variety of clinical presentations, diagnosis of CSD is challenging, especially in the absence of a history of specific exposure. This case report shall remind the physician that cat scratch disease is a common disease, mainly presenting with fever and lymphadenopathy in young patients. Nevertheless CSD has many different and rare forms of presentations, including hepatosplenic lesions and bone involvement as shown in this case. Hindawi Publishing Corporation 2015 2015-10-21 /pmc/articles/PMC4631868/ /pubmed/26576306 http://dx.doi.org/10.1155/2015/317260 Text en Copyright © 2015 D. Knafl et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Knafl, D.
Lötsch, F.
Burgmann, H.
Goliasch, G.
Poeppl, W.
Ramharter, M.
Thalhammer, F.
Schuster, C.
Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease
title Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease
title_full Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease
title_fullStr Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease
title_full_unstemmed Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease
title_short Hepatosplenic Abscesses and Osteomyelitis of the Spine in an Immunocompetent Adult with Cat Scratch Disease
title_sort hepatosplenic abscesses and osteomyelitis of the spine in an immunocompetent adult with cat scratch disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631868/
https://www.ncbi.nlm.nih.gov/pubmed/26576306
http://dx.doi.org/10.1155/2015/317260
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