Cargando…

The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants

Genome-wide association studies (GWAS) have been successfully applied in humans for the study of many complex phenotypes. However, identification of the genetic determinants of hearing in adults has been hampered, in part, by the relative inability to control for environmental factors that might aff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crow, Amanda L., Ohmen, Jeffrey, Wang, Juemei, Lavinsky, Joel, Hartiala, Jaana, Li, Qingzhong, Li, Xin, Salehide, Pezhman, Eskin, Eleazar, Pan, Calvin, Lusis, Aldons J., Allayee, Hooman, Friedman, Rick A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2015
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632053/ https://www.ncbi.nlm.nih.gov/pubmed/26342000 http://dx.doi.org/10.1534/g3.115.021592

Ejemplares similares

The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction
por: Lavinsky, Joel, et al.
Publicado: (2016)

Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss
por: Lavinsky, Joel, et al.
Publicado: (2015)

Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss
por: Lavinsky, Joel, et al.
Publicado: (2015)

The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice
por: Zhou, Xiaoying, et al.
Publicado: (2015)

Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma
por: Han, Yi, et al.
Publicado: (2020)

A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity
por: Maazi, Hadi, et al.
Publicado: (2019)

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains
por: Bennett, Brian J., et al.
Publicado: (2015)

Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains
por: Bennett, Brian J., et al.
Publicado: (2016)

Systems genetics approaches for understanding complex traits with relevance for human disease
por: Allayee, Hooman, et al.
Publicado: (2023)

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits
por: Lusis, Aldons J., et al.
Publicado: (2016)

Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection
por: Hilser, James R., et al.
Publicado: (2021)

Genetic and Clinical Markers of Elevated Liver Fat Content in Overweight and Obese Hispanic Children
por: Walker, Ryan W., et al.
Publicado: (2013)

Systems Genetic Analysis of Osteoblast-Lineage Cells
por: Calabrese, Gina, et al.
Publicado: (2012)

Genetic and environmental control of host-gut microbiota interactions
por: Org, Elin, et al.
Publicado: (2015)

Genetic contribution of the leukotriene pathway to coronary artery disease
por: Hartiala, Jaana, et al.
Publicado: (2011)

Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach
por: Cao, Yang, et al.
Publicado: (2022)

The genetic architecture of NAFLD among inbred strains of mice
por: Hui, Simon T, et al.
Publicado: (2015)

Genetic evidence for independent causal relationships between metabolic biomarkers and risk of coronary artery diseases
por: Allayee, Hooman
Publicado: (2021)

Systems Genetics Analysis of Mouse Chondrocyte Differentiation
por: Suwanwela, Jaijam, et al.
Publicado: (2011)

Quantitative analysis of 3-dimensional facial soft tissue photographic images: technical methods and clinical application
por: Nanda, Vikrum, et al.
Publicado: (2015)

High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping
por: Rau, Christoph D., et al.
Publicado: (2015)

Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation
por: Hartiala, Jaana, et al.
Publicado: (2016)

The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice
por: Hui, Simon T., et al.
Publicado: (2018)

Allele-specific expression and eQTL analysis in mouse adipose tissue
por: Hasin-Brumshtein, Yehudit, et al.
Publicado: (2014)

Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice
por: Huda, M. Nazmul, et al.
Publicado: (2020)

Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1
por: Pirie, Elaine, et al.
Publicado: (2018)

Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose
por: Li, Xia, et al.
Publicado: (2009)

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease
por: Hartiala, Jaana A., et al.
Publicado: (2016)

The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice
por: Tuominen, Iina, et al.
Publicado: (2020)

Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice
por: Drake, Thomas A., et al.
Publicado: (2006)

Gene networks associated with conditional fear in mice identified using a systems genetics approach
por: Park, Christopher C, et al.
Publicado: (2011)

Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy
por: Chella Krishnan, Karthickeyan, et al.
Publicado: (2023)

Isoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis
por: Wang, Jessica, et al.
Publicado: (2019)

Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice
por: Kang, Eun Yong, et al.
Publicado: (2014)

Population structure in genetic studies: Confounding factors and mixed models
por: Sul, Jae Hoon, et al.
Publicado: (2018)

Using genetic markers to orient the edges in quantitative trait networks: The NEO software
por: Aten, Jason E, et al.
Publicado: (2008)

Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery
por: Albright, Jody, et al.
Publicado: (2014)

Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis
por: Farber, Charles R., et al.
Publicado: (2011)

Genetic regulation of mouse liver metabolite levels
por: Ghazalpour, Anatole, et al.
Publicado: (2014)

Hearing difficulty is linked to Alzheimer’s disease by common genetic vulnerability, not shared genetic architecture
por: Abidin, Fatin N. Zainul, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6df7ijl6smg5s794efj9eqs11d