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Exact Inference for Hardy-Weinberg Proportions with Missing Genotypes: Single and Multiple Imputation
This paper addresses the issue of exact-test based statistical inference for Hardy−Weinberg equilibrium in the presence of missing genotype data. Missing genotypes often are discarded when markers are tested for Hardy−Weinberg equilibrium, which can lead to bias in the statistical inference about eq...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632056/ https://www.ncbi.nlm.nih.gov/pubmed/26377959 http://dx.doi.org/10.1534/g3.115.022111 |