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Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin receptor kinase B (TrkB), play a paramount role in the central regulation of energy balance. Despite the substantial body of genetic evidence implicating BDNF- or TrkB-deficiency in human obesity, the critical brain re...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632115/ https://www.ncbi.nlm.nih.gov/pubmed/26629410 http://dx.doi.org/10.1016/j.molmet.2015.08.002 |