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Three simple rules to ensure reasonably credible subgroup analyses

The limitations of subgroup analyses are well established—false positives due to multiple comparisons, false negatives due to inadequate power, and limited ability to inform individual treatment decisions because patients have multiple characteristics that vary simultaneously. In this article, we ap...

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Detalles Bibliográficos
Autores principales: Burke, James F, Sussman, Jeremy B, Kent, David M, Hayward, Rodney A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632208/
https://www.ncbi.nlm.nih.gov/pubmed/26537915
http://dx.doi.org/10.1136/bmj.h5651