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Paracetamol induced Steven-Johnson syndrome: A rare case report

In the contemporary era, use of drugs is the dominant paradigm of health care. The most quotidian drug used for fever and pain is paracetamol. Although adverse reactions to paracetamol in India are rare, at times they can cause life-threatening situations. Stevens-Johnson syndrome (SJS) is one such...

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Autores principales: Rajput, Rajan, Sagari, Shitalkumar, Durgavanshi, Astha, Kanwar, Alpana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632237/
https://www.ncbi.nlm.nih.gov/pubmed/26604588
http://dx.doi.org/10.4103/0976-237X.166838
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author Rajput, Rajan
Sagari, Shitalkumar
Durgavanshi, Astha
Kanwar, Alpana
author_facet Rajput, Rajan
Sagari, Shitalkumar
Durgavanshi, Astha
Kanwar, Alpana
author_sort Rajput, Rajan
collection PubMed
description In the contemporary era, use of drugs is the dominant paradigm of health care. The most quotidian drug used for fever and pain is paracetamol. Although adverse reactions to paracetamol in India are rare, at times they can cause life-threatening situations. Stevens-Johnson syndrome (SJS) is one such potentially lethal adverse drug reaction. The most reported cases of analgesic-induced SJS were due to oxicams or propionic acid derivatives. There are very few detailed reports of SJS due to the use of paracetamol. We report a case of SJS, which occurred due to the use of paracetamol. The clinical features of this condition and multidisciplinary management of the patient are described in brief.
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spelling pubmed-46322372015-11-24 Paracetamol induced Steven-Johnson syndrome: A rare case report Rajput, Rajan Sagari, Shitalkumar Durgavanshi, Astha Kanwar, Alpana Contemp Clin Dent Case Report In the contemporary era, use of drugs is the dominant paradigm of health care. The most quotidian drug used for fever and pain is paracetamol. Although adverse reactions to paracetamol in India are rare, at times they can cause life-threatening situations. Stevens-Johnson syndrome (SJS) is one such potentially lethal adverse drug reaction. The most reported cases of analgesic-induced SJS were due to oxicams or propionic acid derivatives. There are very few detailed reports of SJS due to the use of paracetamol. We report a case of SJS, which occurred due to the use of paracetamol. The clinical features of this condition and multidisciplinary management of the patient are described in brief. Medknow Publications & Media Pvt Ltd 2015-09 /pmc/articles/PMC4632237/ /pubmed/26604588 http://dx.doi.org/10.4103/0976-237X.166838 Text en Copyright: © Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Rajput, Rajan
Sagari, Shitalkumar
Durgavanshi, Astha
Kanwar, Alpana
Paracetamol induced Steven-Johnson syndrome: A rare case report
title Paracetamol induced Steven-Johnson syndrome: A rare case report
title_full Paracetamol induced Steven-Johnson syndrome: A rare case report
title_fullStr Paracetamol induced Steven-Johnson syndrome: A rare case report
title_full_unstemmed Paracetamol induced Steven-Johnson syndrome: A rare case report
title_short Paracetamol induced Steven-Johnson syndrome: A rare case report
title_sort paracetamol induced steven-johnson syndrome: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632237/
https://www.ncbi.nlm.nih.gov/pubmed/26604588
http://dx.doi.org/10.4103/0976-237X.166838
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