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DNA-methylation in C1R is a prognostic biomarker for acute myeloid leukemia

BACKGROUND: Epigenetic aberrations play a central role in the pathophysiology of acute myeloid leukemia (AML). It has been shown that molecular signatures based on DNA-methylation (DNAm) patterns can be used for classification of the disease. In this study, we followed the hypothesis that DNAm at a...

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Detalles Bibliográficos
Autores principales: Božić, Tanja, Lin, Qiong, Frobel, Joana, Wilop, Stefan, Hoffmann, Melanie, Müller-Tidow, Carsten, Brümmendorf, Tim H., Jost, Edgar, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632269/
https://www.ncbi.nlm.nih.gov/pubmed/26539253
http://dx.doi.org/10.1186/s13148-015-0153-6