Cargando…
DNA-methylation in C1R is a prognostic biomarker for acute myeloid leukemia
BACKGROUND: Epigenetic aberrations play a central role in the pathophysiology of acute myeloid leukemia (AML). It has been shown that molecular signatures based on DNA-methylation (DNAm) patterns can be used for classification of the disease. In this study, we followed the hypothesis that DNAm at a...
Autores principales: | Božić, Tanja, Lin, Qiong, Frobel, Joana, Wilop, Stefan, Hoffmann, Melanie, Müller-Tidow, Carsten, Brümmendorf, Tim H., Jost, Edgar, Wagner, Wolfgang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632269/ https://www.ncbi.nlm.nih.gov/pubmed/26539253 http://dx.doi.org/10.1186/s13148-015-0153-6 |
Ejemplares similares
-
Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia
por: Oing, Christoph, et al.
Publicado: (2011) -
Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia
por: Jost, E, et al.
Publicado: (2014) -
Investigation of measurable residual disease in acute myeloid leukemia by DNA methylation patterns
por: Božić, Tanja, et al.
Publicado: (2021) -
A three-gene expression-based risk score can refine the European LeukemiaNet AML classification
por: Wilop, Stefan, et al.
Publicado: (2016) -
Impaired Overall Survival in Young Patients With Acute Myeloid Leukemia and Variants in Genes Predisposing for Myeloid Malignancies
por: Kirschner, Martin, et al.
Publicado: (2022)