Cargando…

RAC3 more than a nuclear receptor coactivator: a key inhibitor of senescence that is downregulated in aging

Receptor-associated coactivator 3 (RAC3) is a nuclear receptor coactivator usually overexpressed in tumors that exerts oncogenic functions in the cytoplasm and the nucleus. Although as part of its oncogenic actions it was previously identified as an inhibitor of apoptosis and autophagy, its expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernández Larrosa, P N, Ruíz Grecco, M, Mengual Gómez, D, Alvarado, C V, Panelo, L C, Rubio, M F, Alonso, D F, Gómez, D E, Costas, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632280/
https://www.ncbi.nlm.nih.gov/pubmed/26469953
http://dx.doi.org/10.1038/cddis.2015.218