Cargando…
RAC3 more than a nuclear receptor coactivator: a key inhibitor of senescence that is downregulated in aging
Receptor-associated coactivator 3 (RAC3) is a nuclear receptor coactivator usually overexpressed in tumors that exerts oncogenic functions in the cytoplasm and the nucleus. Although as part of its oncogenic actions it was previously identified as an inhibitor of apoptosis and autophagy, its expressi...
Autores principales: | Fernández Larrosa, P N, Ruíz Grecco, M, Mengual Gómez, D, Alvarado, C V, Panelo, L C, Rubio, M F, Alonso, D F, Gómez, D E, Costas, M A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632280/ https://www.ncbi.nlm.nih.gov/pubmed/26469953 http://dx.doi.org/10.1038/cddis.2015.218 |
Ejemplares similares
-
Role of RAC3 coactivator in the adipocyte differentiation
por: Lira, María Cecilia, et al.
Publicado: (2018) -
The levels of RAC3 expression are up regulated by TNF in the inflammatory response
por: Alvarado, Cecilia Viviana, et al.
Publicado: (2014) -
High RAC3 expression levels are required for induction and maintaining of cancer cell stemness
por: Panelo, Laura C., et al.
Publicado: (2017) -
Corepressor/coactivator paradox: potential constitutive coactivation by corepressor splice variants
por: Meng, Xianwang, et al.
Publicado: (2006) -
The inflammatory cytokine TNF contributes with RAC3-induced malignant transformation
por: Machado, Mileni Soares, et al.
Publicado: (2018)