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Caspase-8 activation by TRAIL monotherapy predicts responses to IAPi and TRAIL combination treatment in breast cancer cell lines

The discovery of cancer cell-selective tumour necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis generated broad excitement and development of TRAIL receptor agonists (TRA) as potential cancer therapy. Studies demonstrating the synergistic combination effect of SMAC mimetics...

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Detalles Bibliográficos
Autores principales:	Polanski, R, Vincent, J, Polanska, U M, Petreus, T, Tang, E K Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632282/ https://www.ncbi.nlm.nih.gov/pubmed/26426685 http://dx.doi.org/10.1038/cddis.2015.234

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