Cargando…

Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation

Primary cilia are antenna-like structures projected from the apical surface of various mammalian cells including renal tubular cells. Functional or structural defects of the cilium lead to systemic disorders comprising polycystic kidneys as a key feature. Here we show that anoctamin 6 (ANO6), a memb...

Descripción completa

Detalles Bibliográficos
Autores principales: Forschbach, V, Goppelt-Struebe, M, Kunzelmann, K, Schreiber, R, Piedagnel, R, Kraus, A, Eckardt, K-U, Buchholz, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632301/
https://www.ncbi.nlm.nih.gov/pubmed/26448322
http://dx.doi.org/10.1038/cddis.2015.273