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Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation
Primary cilia are antenna-like structures projected from the apical surface of various mammalian cells including renal tubular cells. Functional or structural defects of the cilium lead to systemic disorders comprising polycystic kidneys as a key feature. Here we show that anoctamin 6 (ANO6), a memb...
Autores principales: | Forschbach, V, Goppelt-Struebe, M, Kunzelmann, K, Schreiber, R, Piedagnel, R, Kraus, A, Eckardt, K-U, Buchholz, B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632301/ https://www.ncbi.nlm.nih.gov/pubmed/26448322 http://dx.doi.org/10.1038/cddis.2015.273 |
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