Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma

Acute glaucoma is a leading cause of irreversible blindness in East Asia. The mechanisms underlying retinal neuronal injury induced by a sudden rise in intraocular pressure (IOP) remain obscure. Here we demonstrate that the activation of CXCL10/CXCR3 axis, which mediates the recruitment and activati...

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Detalles Bibliográficos
Autores principales: Ha, Y, Liu, H, Xu, Z, Yokota, H, Narayanan, S P, Lemtalsi, T, Smith, S B, Caldwell, R W, Caldwell, R B, Zhang, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632306/
https://www.ncbi.nlm.nih.gov/pubmed/26448323
http://dx.doi.org/10.1038/cddis.2015.281

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