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Detection of genetic variation using dual-labeled peptide nucleic acid (PNA) probe-based melting point analysis

BACKGROUND: Thermal denaturation of probe-target hybrid is highly reproducible, and which makes probe melting point analysis reliable in the detection of mutations, polymorphisms and epigenetic differences in DNA. To improve resolution of these detections, we used dual-labeled (quencher and fluoresc...

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Detalles Bibliográficos
Autores principales:	Hur, Deokhwe, Kim, Myoung Sug, Song, Minsik, Jung, Jinwook, Park, Heekyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632671/ https://www.ncbi.nlm.nih.gov/pubmed/26539063 http://dx.doi.org/10.1186/s12575-015-0027-5

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