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Genome Editing Using Mammalian Haploid Cells

Haploid cells are useful for studying gene functions because disruption of a single allele can cause loss-of-function phenotypes. Recent success in generating haploid embryonic stem cells (ESCs) in mice, rats, and monkeys provides a new platform for simple genetic manipulation of the mammalian genom...

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Detalles Bibliográficos
Autores principales:	Horii, Takuro, Hatada, Izuho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632716/ https://www.ncbi.nlm.nih.gov/pubmed/26437403 http://dx.doi.org/10.3390/ijms161023604

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