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Expression of Vitamin D Receptor (VDR) Positively Correlates with Survival of Urothelial Bladder Cancer Patients

Vitamin D3 shows tumoristatic and anticancer effects by acting through the vitamin D receptor (VDR), while hydroxylation of 25-hydroxyvitamin D3 at position 1α by CYP27B1 is an essential step in its activation. The expression of both the VDR and CYP27B1 has been found in many normal and cancer tissu...

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Detalles Bibliográficos
Autores principales: Jóźwicki, Wojciech, Brożyna, Anna A., Siekiera, Jerzy, Slominski, Andrzej T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632755/
https://www.ncbi.nlm.nih.gov/pubmed/26501255
http://dx.doi.org/10.3390/ijms161024369