Studies on [5,6]-Fused Bicyclic Scaffolds Derivatives as Potent Dual B-Raf(V600E)/KDR Inhibitors Using Docking and 3D-QSAR Approaches

Research and development of multi-target inhibitors has attracted increasing attention as anticancer therapeutics. B-Raf(V600E) synergistically works with vascular endothelial growth factor receptor 2 (KDR) to promote the occurrence and progression of cancers, and the development of dual-target drug...

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Detalles Bibliográficos
Autores principales: Liu, Hai-Chun, Tang, San-Zhi, Lu, Shuai, Ran, Ting, Wang, Jian, Zhang, Yan-Min, Xu, An-Yang, Lu, Tao, Chen, Ya-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632759/
https://www.ncbi.nlm.nih.gov/pubmed/26501259
http://dx.doi.org/10.3390/ijms161024451

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