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Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma

Accumulating evidence shows that activity of the pyruvate kinase M2 (PKM2) isoform is closely related to tumorigenesis. In this study, we investigated the relationship betweenPKM2 expression, tumor invasion, and the prognosis of patients with lung adenocarcinoma. We retrospectively analyzed 65 cases...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Zhu, Anyou, Zhang, Lunjun, Zhang, Jie, Zhong, Zhengrong, Wang, Fengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632765/
https://www.ncbi.nlm.nih.gov/pubmed/26501265
http://dx.doi.org/10.3390/ijms161024574