Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases

Programmable nucleases, such as zinc finger nucleases (ZFNs), transcription activator like effector nucleases (TALENs), and clustered regularly interspersed short palindromic repeats associated protein-9 (CRISPR-Cas9), hold tremendous potential for applications in the clinical setting to treat genet...

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Detalles Bibliográficos
Autores principales: Ishida, Kentaro, Gee, Peter, Hotta, Akitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632775/
https://www.ncbi.nlm.nih.gov/pubmed/26501275
http://dx.doi.org/10.3390/ijms161024751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632775/
https://www.ncbi.nlm.nih.gov/pubmed/26501275
http://dx.doi.org/10.3390/ijms161024751

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