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Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases

Programmable nucleases, such as zinc finger nucleases (ZFNs), transcription activator like effector nucleases (TALENs), and clustered regularly interspersed short palindromic repeats associated protein-9 (CRISPR-Cas9), hold tremendous potential for applications in the clinical setting to treat genet...

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Detalles Bibliográficos
Autores principales:	Ishida, Kentaro, Gee, Peter, Hotta, Akitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632775/ https://www.ncbi.nlm.nih.gov/pubmed/26501275 http://dx.doi.org/10.3390/ijms161024751

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