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PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway
Poly(ADP-ribosyl)ation is known to be involved in a variety of cellular processes, such as DNA repair, cell death, telomere regulation, genomic stability and cell differentiation by poly(ADP-ribose) polymerase (PARP). While PARP inhibitors are presently under clinical investigation for cancer therap...
Autores principales: | Kishi, Yuta, Fujihara, Hisako, Kawaguchi, Koji, Yamada, Hiroyuki, Nakayama, Ryoko, Yamamoto, Nanami, Fujihara, Yuko, Hamada, Yoshiki, Satomura, Kazuhito, Masutani, Mitsuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632778/ https://www.ncbi.nlm.nih.gov/pubmed/26492236 http://dx.doi.org/10.3390/ijms161024820 |
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