Cargando…

The Fab Fragment of a Humanized Anti-Toll Like Receptor 4 (TLR4) Monoclonal Antibody Reduces the Lipopolysaccharide Response via TLR4 in Mouse Macrophages

Lipopolysaccharides (LPS) can induce acute inflammation, sepsis, or chronic inflammatory disorders through the Toll receptor 4 (TLR4) signaling pathway. The TLR4/MD2 (myeloid differentiation protein 2) complex plays a major role in the immune response to LPS. However, there is not a good method to s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Binggang, Wang, Maorong, Zhu, Xuhui, Xu, Jing, Zheng, Wenkai, Zhang, Yiqing, Zheng, Feng, Feng, Zhenqing, Zhu, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632812/ https://www.ncbi.nlm.nih.gov/pubmed/26512658 http://dx.doi.org/10.3390/ijms161025502

Ejemplares similares

A Human Anti-Toll Like Receptor 4 Fab Fragment Inhibits Lipopolysaccharide-Induced Pro-Inflammatory Cytokines Production in Macrophages
por: Wang, Maorong, et al.
Publicado: (2016)

Human monoclonal anti-TLR4 antibody negatively regulates lipopolysaccharide-induced inflammatory responses in mouse macrophages
por: Wang, Yiwen, et al.
Publicado: (2020)

The Fab Fragment of a Human Anti-Siglec-9 Monoclonal Antibody Suppresses LPS-Induced Inflammatory Responses in Human Macrophages
por: Chu, Sasa, et al.
Publicado: (2016)

The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll-Like Receptor 4 (TLR4) Signalling
por: Cochet, Florent, et al.
Publicado: (2017)

Humanized anti-TLR4 monoclonal antibody ameliorates lipopolysaccharide-related acute kidney injury by inhibiting TLR4/NF-κB signaling
por: Zhang, Qiuhua, et al.
Publicado: (2021)

Recognition of lipopolysaccharide pattern by TLR4 complexes
por: Park, Beom Seok, et al.
Publicado: (2013)

Toll-Like Receptor 4 (TLR4) and Typhoid Fever in Vietnam
por: Hue, Nguyen Thi, et al.
Publicado: (2009)

Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease
por: Budulac, Simona E., et al.
Publicado: (2012)

Expression of Toll-Like Receptors (TLR2 and TLR4) in the Eyes of Mice with Disseminated Acanthamoebiasis
por: Kot, Karolina, et al.
Publicado: (2019)

TLR2 and TLR4 in Parkinson’s disease pathogenesis: the environment takes a toll on the gut
por: Gorecki, Anastazja M., et al.
Publicado: (2021)

Toll-Like Receptor 4 (TLR4) Expression Affects Schwann Cell Behavior in vitro
por: Zhang, Huanhuan, et al.
Publicado: (2018)

Kukoamine B promotes TLR4-independent lipopolysaccharide uptake in murine hepatocytes
por: Yang, Dong, et al.
Publicado: (2016)

Phylogenetic variation and polymorphism at the Toll-like receptor 4 locus (TLR4)
por: Smirnova, Irina, et al.
Publicado: (2000)

Toll-Like Receptor 4 (TLR4) and AMPK Relevance in Cardiovascular Disease
por: Vaez, Haleh, et al.
Publicado: (2023)

Toll-like receptor 4 (TLR4): new insight immune and aging
por: Kim, Hyo-Jin, et al.
Publicado: (2023)

A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses
por: Takahashi, Koichiro, et al.
Publicado: (2007)

Toll-Like Receptor (TLR) 2 and TLR4 Differentially Regulate Doxorubicin Induced Cardiomyopathy in Mice
por: Ma, Yonggang, et al.
Publicado: (2012)

Clinical Implication of Toll-Like Receptors (TLR2 and TLR4) in Acute Myeloid Leukemia Patients
por: Aref, Salah, et al.
Publicado: (2020)

Modulation of TLR2 and TLR4 in Macrophages Following Trichinella Spiralis Infection
por: Han, C., et al.
Publicado: (2018)

miRNA-Induced Downregulation of IPMK in Macrophages Mediates Lipopolysaccharide-Triggered TLR4 Signaling
por: Lee, Haein, et al.
Publicado: (2023)

Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)
por: Qureshi, Salman T., et al.
Publicado: (1999)

Toll-like receptor 4 (TLR4) antagonists as potential therapeutics for intestinal inflammation
por: Tam, Janine S. Y., et al.
Publicado: (2021)

Phytochemicals targeting Toll-like receptors 4 (TLR4) in inflammatory bowel disease
por: Dai, Wenbin, et al.
Publicado: (2022)

Oxy210, a Semi-Synthetic Oxysterol, Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization
por: Wang, Feng, et al.
Publicado: (2022)

Association between TLR4 and PTEN Involved in LPS-TLR4 Signaling Response
por: Yin, Huahua, et al.
Publicado: (2016)

Combination with Toll-like receptor 4 (TLR4) agonist reverses GITR agonism mediated M2 polarization of macrophage in Hepatocellular carcinoma
por: Pan, Caixu, et al.
Publicado: (2022)

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis
por: Lima, Cristiano Xavier, et al.
Publicado: (2015)

IL-1-driven cartilage and bone destruction are dependent on Toll-like receptor (TLR) 4, but not TLR2
por: Abdollahi-Roodsaz, S, et al.
Publicado: (2005)

Contrasted evolutionary histories of two Toll-like receptors (Tlr4 and Tlr7) in wild rodents (MURINAE)
por: Fornůsková, Alena, et al.
Publicado: (2013)

Correction: Toll-Like Receptor (TLR) 2 and TLR4 Differentially Regulate Doxorubicin Induced Cardiomyopathy in Mice
por: Ma, Yonggang, et al.
Publicado: (2012)

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases
por: ten Oever, Jaap, et al.
Publicado: (2014)

Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways
por: Zamyatina, Alla, et al.
Publicado: (2020)

Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists Rhodobacter sphaeroides Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2
por: Rallabhandi, Prasad, et al.
Publicado: (2012)

Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function
por: Stephens, Matthew, et al.
Publicado: (2021)

Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis
por: Kim, Geun-Tae, et al.
Publicado: (2009)

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
por: Roshan, Mohsin H. K., et al.
Publicado: (2016)

FDA Approved Drugs Repurposing of Toll-Like Receptor4 (TLR4) Candidate for Neuropathy
por: Zali, Hakimeh, et al.
Publicado: (2019)

Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages
por: Palmer, Charys, et al.
Publicado: (2021)

Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity
por: Ji, Yewei, et al.
Publicado: (2019)

Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway
por: Lucas, Kurt, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_38fgsj5sd9hq00d3heb36ojs2j