Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells

Antibody-dependent cellular cytotoxicity (ADCC), a key effector function for the clinical effectiveness of monoclonal antibodies, is triggered by the engagement of the antibody Fc domain with the Fcγ receptors expressed by innate immune cells such as natural killer (NK) cells and macrophages. Here,...

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Detalles Bibliográficos
Autores principales: Sioud, Mouldy, Westby, Phuong, Olsen, Julie Kristine E., Mobergslien, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632835/
https://www.ncbi.nlm.nih.gov/pubmed/26605373
http://dx.doi.org/10.1038/mtm.2015.43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632835/
https://www.ncbi.nlm.nih.gov/pubmed/26605373
http://dx.doi.org/10.1038/mtm.2015.43

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