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Activated estrogen receptor-mitogen-activated protein kinases cross talk confer acquired resistance to lapatinib

BACKGROUND: The efficacy of lapatinib is limited by the development of acquired resistance. The aim of this study was to investigate the role of estrogen receptor (ER) signaling compensatory activation in acquired resistance to lapatinib in breast cancer cells BT474 and the related mechanism. METHOD...

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Detalles Bibliográficos
Autores principales:	Li, Zhe, Yang, Sheng-Sheng, Yin, Pei-Hao, Chang, Tao, Shi, Lin-Xiang, Fang, Lin, Fang, Guo-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632920/ https://www.ncbi.nlm.nih.gov/pubmed/26557906 http://dx.doi.org/10.1111/1759-7714.12239

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