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Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy

Chemotherapy often fails due to cellular detoxifying mechanisms, including phase-II enzymes. Activation of Nrf2-Keap1 pathway induces phase-II enzymes expression through ARE-signaling and prevents cancer development. Nrf2-overexpression in cancer cells results in chemo- and/or radioresistance. This...

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Detalles Bibliográficos
Autores principales:	Foygel, Kira, Sekar, Thillai V., Paulmurugan, Ramasamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633093/ https://www.ncbi.nlm.nih.gov/pubmed/26536456 http://dx.doi.org/10.1371/journal.pone.0141913

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