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Drug Transporter Genetic Variants Are Not Associated with TDF-Related Renal Dysfunction in Patients with HIV-1 Infection: A Pharmacogenetic Study
OBJECTIVE: To investigate whether single nucleotide polymorphisms (SNP) of drug transporter proteins for TDF is a risk factor for TDF-related renal function decrement. METHODS: This study investigated the association between 3 SNPs (ABCC2–24, 1249, and ABCB1 2677), which are shown to be associated w...
Autores principales: | Nishijima, Takeshi, Hayashida, Tsunefusa, Kurosawa, Takuma, Tanaka, Noriko, Oka, Shinichi, Gatanaga, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633171/ https://www.ncbi.nlm.nih.gov/pubmed/26535588 http://dx.doi.org/10.1371/journal.pone.0141931 |
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