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SOX2 and SOX2-MYC Reprogramming Process of Fibroblasts to the Neural Stem Cells Compromised by Senescence

Tumorigenic potential of induced pluripotent stem cells (iPSCs) infiltrating population of induced neural stem cells (iNSCs) generated from iPSCs may limit their medical applications. To overcome such a difficulty, direct reprogramming of adult somatic cells into iNSCs was proposed. The aim of this...

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Detalles Bibliográficos
Autores principales:	Winiecka-Klimek, Marta, Smolarz, Maciej, Walczak, Maciej P., Zieba, Jolanta, Hulas-Bigoszewska, Krystyna, Kmieciak, Blazej, Piaskowski, Sylwester, Rieske, Piotr, Grzela, Dawid P., Stoczynska-Fidelus, Ewelina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633175/ https://www.ncbi.nlm.nih.gov/pubmed/26535892 http://dx.doi.org/10.1371/journal.pone.0141688

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