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Cell Lysis in S. pombe ura4 Mutants Is Suppressed by Loss of Functional Pub1, Which Regulates the Uracil Transporter Fur4

Schizosaccharomyces pombe Δura4 cells lyse when grown on YPD medium. A S. pombe non-essential gene deletion library was screened to determine suppressors of the lysis phenotype. Deletion of the pub1 gene, which encoded E3 ubiquitin ligase, strongly suppressed cell lysis in Δura4 cells. The Δpub1 cel...

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Detalles Bibliográficos
Autores principales: Nishino, Kohei, Kushima, Misaki, Matsuo, Yuzy, Matsuo, Yasuhiro, Kawamukai, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633276/
https://www.ncbi.nlm.nih.gov/pubmed/26536126
http://dx.doi.org/10.1371/journal.pone.0141796

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