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Demonstration of Therapeutic Equivalence of Fluconazole Generic Products in the Neutropenic Mouse Model of Disseminated Candidiasis

Some generics of antibacterials fail therapeutic equivalence despite being pharmaceutical equivalents of their innovators, but data are scarce with antifungals. We used the neutropenic mice model of disseminated candidiasis to challenge the therapeutic equivalence of three generic products of flucon...

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Detalles Bibliográficos
Autores principales: Gonzalez, Javier M., Rodriguez, Carlos A., Zuluaga, Andres F., Agudelo, Maria, Vesga, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633286/
https://www.ncbi.nlm.nih.gov/pubmed/26536105
http://dx.doi.org/10.1371/journal.pone.0141872