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Targeting Leukemia Stem Cells in vivo with AntagomiR-126 Nanoparticles in Acute Myeloid Leukemia

Current treatments for acute myeloid leukemia (AML) are designed to target rapidly dividing blast populations with limited success in eradicating the functionally distinct leukemia stem cell (LSC) population, which is postulated to be responsible for disease resistance and relapse. We have previousl...

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Detalles Bibliográficos
Autores principales: Dorrance, Adrienne M., Neviani, Paolo, Ferenchak, Greg J., Huang, Xiaomeng, Nicolet, Deedra, Maharry, Kati S., Ozer, Hatice G, Hoellarbauer, Pia, Khalife, Jihane, Hill, Emily B., Yadav, Marshleen, Bolon, Brad N., Lee, Robert J., Lee, L.James, Croce, Carlo M., Garzon, Ramiro, Caligiuri, Michael A., Bloomfield, Clara D., Marcucci., Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633325/
https://www.ncbi.nlm.nih.gov/pubmed/26055302
http://dx.doi.org/10.1038/leu.2015.139