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Targeting Leukemia Stem Cells in vivo with AntagomiR-126 Nanoparticles in Acute Myeloid Leukemia
Current treatments for acute myeloid leukemia (AML) are designed to target rapidly dividing blast populations with limited success in eradicating the functionally distinct leukemia stem cell (LSC) population, which is postulated to be responsible for disease resistance and relapse. We have previousl...
Autores principales: | Dorrance, Adrienne M., Neviani, Paolo, Ferenchak, Greg J., Huang, Xiaomeng, Nicolet, Deedra, Maharry, Kati S., Ozer, Hatice G, Hoellarbauer, Pia, Khalife, Jihane, Hill, Emily B., Yadav, Marshleen, Bolon, Brad N., Lee, Robert J., Lee, L.James, Croce, Carlo M., Garzon, Ramiro, Caligiuri, Michael A., Bloomfield, Clara D., Marcucci., Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633325/ https://www.ncbi.nlm.nih.gov/pubmed/26055302 http://dx.doi.org/10.1038/leu.2015.139 |
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