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Regulation of cardiac miR-208a, an inducer of obesity, by Rapamycin and Nebivolol
OBJECTIVE: Resistance to obesity is observed in rodents and humans treated with Rapamycin (Rap) or Nebivolol (Neb). Since cardiac miR-208a promotes obesity, we tested whether the modes of actions of Rap and Neb involve inhibition of miR-208a. METHODS: Mouse cardiomyocyte HL-1 cells and Zucker obese...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633375/ https://www.ncbi.nlm.nih.gov/pubmed/26381051 http://dx.doi.org/10.1002/oby.21227 |