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Understanding the Basics of NGS: From Mechanism to Variant Calling
Identifying disease-causing mutations in DNA has long been the goal of genetic medicine. In the last decade, the toolkit for discovering DNA variants has undergone rapid evolution: mutations that were historically discovered by analog approaches like Sanger sequencing and multiplex ligation-dependen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633438/ https://www.ncbi.nlm.nih.gov/pubmed/26566462 http://dx.doi.org/10.1007/s40142-015-0076-8 |