Cargando…

Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways

Aortic valve calcification (AVC), which used to be recognized as a passive and irreversible process, is now widely accepted as an active and regulated process characterized by osteoblastic differentiation of aortic valve interstitial cells (AVICs). Apelin, the endogenous ligand for G-protein-coupled...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Zhao-shun, Zhou, Yang-zhao, Liao, Xiao-bo, Luo, Jia-wen, Shen, Kang-jun, Hu, Ye-rong, Gu, Lu, Li, Jian-ming, Tan, Chang-ming, Chen, He-ming, Zhou, Xin-min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Vienna 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633450/ https://www.ncbi.nlm.nih.gov/pubmed/26142632 http://dx.doi.org/10.1007/s00726-015-2020-3

Ejemplares similares

Apelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells
por: Shan, Peng-Fei, et al.
Publicado: (2011)

miR-214 Attenuates Aortic Valve Calcification by Regulating Osteogenic Differentiation of Valvular Interstitial Cells
por: Li, Ning, et al.
Publicado: (2020)

The Natural Product Andrographolide Ameliorates Calcific Aortic Valve Disease by Regulating the Proliferation of Valve Interstitial Cells via the MAPK-ERK Pathway
por: Huang, Yuming, et al.
Publicado: (2022)

Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way
por: En, Qiao, et al.
Publicado: (2021)

Apelin-13 Is an Early Promoter of Cytoskeleton and Tight Junction in Diabetic Macular Edema via PI-3K/Akt and MAPK/Erk Signaling Pathways
por: Li, Yang, et al.
Publicado: (2018)

N-Cadherin Negatively Regulates Osteoblast Proliferation and Survival by Antagonizing Wnt, ERK and PI3K/Akt Signalling
por: Haÿ, Eric, et al.
Publicado: (2009)

Adiponectin Induces Oncostatin M Expression in Osteoblasts through the PI3K/Akt Signaling Pathway
por: Su, Chen-Ming, et al.
Publicado: (2015)

ECFC-derived exosomal THBS1 mediates angiogenesis and osteogenesis in distraction osteogenesis via the PI3K/AKT/ERK pathway
por: Liao, Fengchun, et al.
Publicado: (2022)

Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway
por: Yang, Keda, et al.
Publicado: (2021)

Apelin-13 induces proliferation, migration, and collagen I mRNA expression in human RPE cells via PI3K/Akt and MEK/Erk signaling pathways
por: Qin, Dong, et al.
Publicado: (2013)

Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway
por: Zhao, Yu, et al.
Publicado: (2020)

Oroxylin A attenuates IL-1β-induced inflammatory reaction via inhibiting the activation of the ERK and PI3K/AKT signaling pathways in osteoarthritis chondrocytes
por: Zhang, Yong, et al.
Publicado: (2021)

Effects of evodiamine on PI3K/Akt and MAPK/ERK signaling pathways in pancreatic cancer cells
por: Hong, Zhong, et al.
Publicado: (2020)

Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of enterovirus 71
por: Wong, Wen-Rou, et al.
Publicado: (2005)

Semaphorin 4D is a potential biomarker in pediatric leukemia and promotes leukemogenesis by activating PI3K/AKT and ERK signaling pathways
por: Jiang, Hongchao, et al.
Publicado: (2021)

Apelin-13 alleviated cardiac fibrosis via inhibiting the PI3K/Akt pathway to attenuate oxidative stress in rats with myocardial infarction-induced heart failure
por: Zhong, Shan, et al.
Publicado: (2020)

Omentin-1 Stimulates Human Osteoblast Proliferation through PI3K/Akt Signal Pathway
por: Wu, Shan-Shan, et al.
Publicado: (2013)

The Impact of Transcatheter Aortic Valve Implantation (TAVI) on Serum Apelin Levels in Patients with Aortic Valvular Stenosis
por: Kucukosmanoglu, Mehmet, et al.
Publicado: (2021)

Galangin ameliorates cardiac remodeling via the MEK1/2–ERK1/2 and PI3K–AKT pathways
por: Wang, Hui‐Bo, et al.
Publicado: (2019)

Ghrelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells through the ERK Pathway
por: Liang, Qiu-Hua, et al.
Publicado: (2012)

Leonurine Promotes the Osteoblast Differentiation of Rat BMSCs by Activation of Autophagy via the PI3K/Akt/mTOR Pathway
por: Zhao, Bingkun, et al.
Publicado: (2021)

Fenofibrate Attenuated Glucose-Induced Mesangial Cells Proliferation and Extracellular Matrix Synthesis via PI3K/AKT and ERK1/2
por: Zeng, Rui, et al.
Publicado: (2013)

Comparison of Rapidly Proliferating, Multipotent Aortic Valve-Derived Stromal Cells and Valve Interstitial Cells in the Human Aortic Valve
por: Huang, Yuming, et al.
Publicado: (2019)

High fructose induced osteogenic differentiation of human valve interstitial cells via activating PI3K/AKT/mitochondria signaling
por: Chang, Hsiao-Huang, et al.
Publicado: (2022)

The protective effect of Apelin-13 against cardiac hypertrophy through activating the PI3K-AKT-mTOR signaling pathway
por: Peng, Yu, et al.
Publicado: (2023)

Caffeic Acid Phenethyl Ester Ameliorates Calcification by Inhibiting Activation of the AKT/NF-κB/NLRP3 Inflammasome Pathway in Human Aortic Valve Interstitial Cells
por: Liu, Ming, et al.
Publicado: (2020)

Si-Wu-tang extract stimulates bone formation through PI3K/Akt/NF-κB signaling pathways in osteoblasts
por: Wu, Chi-Ming, et al.
Publicado: (2013)

The ILEI/LIFR complex induces EMT via the Akt and ERK pathways in renal interstitial fibrosis
por: Zhou, Jieqing, et al.
Publicado: (2022)

Gli1 promotes the phenotypic transformation of valve interstitial cells through Hedgehog pathway activation exacerbating calcific aortic valve disease
por: Huang, Yuming, et al.
Publicado: (2023)

Crosstalk Between MAPK/ERK and PI3K/AKT Signal Pathways During Brain Ischemia/Reperfusion
por: Zhou, Jing, et al.
Publicado: (2015)

Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways
por: Liao, Zhiheng, et al.
Publicado: (2022)

The research on lapatinib in autophagy, cell cycle arrest and epithelial to mesenchymal transition via Wnt/ErK/PI3K-AKT signaling pathway in human cutaneous squamous cell carcinoma
por: Yao, Ming, et al.
Publicado: (2017)

33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways
por: Guo, Chunmei, et al.
Publicado: (2020)

CRLF1 promotes malignant phenotypes of papillary thyroid carcinoma by activating the MAPK/ERK and PI3K/AKT pathways
por: Yu, Shi-Tong, et al.
Publicado: (2018)

Qingjie Fuzheng granules inhibit colorectal cancer cell growth by the PI3K/AKT and ERK pathways
por: Yang, Hong, et al.
Publicado: (2019)

NETO2 promotes esophageal cancer progression by inducing proliferation and metastasis via PI3K/AKT and ERK pathway
por: Xu, Jia-cheng, et al.
Publicado: (2021)

Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification
por: Gu, Jia, et al.
Publicado: (2019)

Hydroxysafflor yellow A inhibited lipopolysaccharide‐induced non‐small cell lung cancer cell proliferation, migration, and invasion by suppressing the PI3K/AKT/mTOR and ERK/MAPK signaling pathways
por: Jiang, Ming, et al.
Publicado: (2019)

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer
por: Shafei, Mai Ahmed, et al.
Publicado: (2020)

Ginsenoside-Rd Promotes Neurite Outgrowth of PC12 Cells through MAPK/ERK- and PI3K/AKT-Dependent Pathways
por: Wu, Song-Di, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_l1vomd5hgjh9qnre8uen1v1627