Ape parasite origins of human malaria virulence genes

Antigens encoded by the var gene family are major virulence factors of the human malaria parasite Plasmodium falciparum, exhibiting enormous intra- and interstrain diversity. Here we use network analysis to show that var architecture and mosaicism are conserved at multiple levels across the Laverani...

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Detalles Bibliográficos
Autores principales: Larremore, Daniel B., Sundararaman, Sesh A., Liu, Weimin, Proto, William R., Clauset, Aaron, Loy, Dorothy E., Speede, Sheri, Plenderleith, Lindsey J., Sharp, Paul M., Hahn, Beatrice H., Rayner, Julian C., Buckee, Caroline O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633637/
https://www.ncbi.nlm.nih.gov/pubmed/26456841
http://dx.doi.org/10.1038/ncomms9368

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