Cargando…
Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence
Streptococcus pneumoniae is a major cause of life-threatening diseases worldwide. Here we provide an in-depth functional characterization of LytB, the peptidoglycan hydrolase responsible for physical separation of daughter cells. Identified herein as an N-acetylglucosaminidase, LytB is involved also...
Autores principales: | Rico-Lastres, Palma, Díez-Martínez, Roberto, Iglesias-Bexiga, Manuel, Bustamante, Noemí, Aldridge, Christine, Hesek, Dusan, Lee, Mijoon, Mobashery, Shahriar, Gray, Joe, Vollmer, Waldemar, García, Pedro, Menéndez, Margarita |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633669/ https://www.ncbi.nlm.nih.gov/pubmed/26537571 http://dx.doi.org/10.1038/srep16198 |
Ejemplares similares
-
Identification of the chain-dispersing peptidoglycan hydrolase LytB of Streptococcus gordonii
por: Arrigucci, Riccardo, et al.
Publicado: (2017) -
LytB1 and LytB2 of Mycobacterium tuberculosis Are Not Genetically Redundant
por: Brown, Amanda Claire, et al.
Publicado: (2015) -
Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae
por: Mellroth, Peter, et al.
Publicado: (2014) -
Nasopharyngeal Colonization and Invasive Disease Are Enhanced by the Cell Wall Hydrolases LytB and LytC of Streptococcus pneumoniae
por: Ramos-Sevillano, Elisa, et al.
Publicado: (2011) -
Horizontal-Acquisition of a Promiscuous Peptidoglycan-Recycling Enzyme Enables Aphids To Influence Symbiont Cell Wall Metabolism
por: Smith, Thomas E., et al.
Publicado: (2021)