Targeting HER-3 to elicit antitumor helper T cells against head and neck squamous cell carcinoma

HER-3 expression has been reported to act as an important oncoprotein in head and neck squamous cell carcinoma. This protein is known to control tumor proliferation and acquisition of resistance by tumor cells towards EGFR inhibitors, therefore, development of a HER-3-targeted therapy is desirable....

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Detalles Bibliográficos
Autores principales: Kumai, Takumi, Ohkuri, Takayuki, Nagato, Toshihiro, Matsuda, Yoshinari, Oikawa, Kensuke, Aoki, Naoko, Kimura, Shoji, Celis, Esteban, Harabuchi, Yasuaki, Kobayashi, Hiroya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633732/
https://www.ncbi.nlm.nih.gov/pubmed/26538233
http://dx.doi.org/10.1038/srep16280

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