Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function

Assembly and maturation of synapses at the Drosophila neuromuscular junction (NMJ) depend on trans-synaptic neurexin/neuroligin signalling, which is promoted by the scaffolding protein Syd-1 binding to neurexin. Here we report that the scaffold protein spinophilin binds to the C-terminal portion of...

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Detalles Bibliográficos
Autores principales: Muhammad, Karzan, Reddy-Alla, Suneel, Driller, Jan H, Schreiner, Dietmar, Rey, Ulises, Böhme, Mathias A., Hollmann, Christina, Ramesh, Niraja, Depner, Harald, Lützkendorf, Janine, Matkovic, Tanja, Götz, Torsten, Bergeron, Dominique D., Schmoranzer, Jan, Goettfert, Fabian, Holt, Mathew, Wahl, Markus C., Hell, Stefan W., Scheiffele, Peter, Walter, Alexander M., Loll, Bernhard, Sigrist, Stephan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633989/
https://www.ncbi.nlm.nih.gov/pubmed/26471740
http://dx.doi.org/10.1038/ncomms9362

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