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Activation and lysis of human CD4 cells latently infected with HIV-1

The treatment of AIDS with combination antiretroviral therapy (cART) remains lifelong largely because the virus persists in latent reservoirs. Elimination of latently infected cells could therefore reduce treatment duration and facilitate immune reconstitution. Here we report an approach to reduce t...

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Detalles Bibliográficos
Autores principales: Pegu, Amarendra, Asokan, Mangaiarkarasi, Wu, Lan, Wang, Keyun, Hataye, Jason, Casazza, Joseph P., Guo, Xiaoti, Shi, Wei, Georgiev, Ivelin, Zhou, Tongqing, Chen, Xuejun, O'Dell, Sijy, Todd, John-Paul, Kwong, Peter D., Rao, Srinivas S., Yang, Zhi-yong, Koup, Richard A., Mascola, John R., Nabel, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633990/
https://www.ncbi.nlm.nih.gov/pubmed/26485194
http://dx.doi.org/10.1038/ncomms9447

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