IRSp53 senses negative membrane curvature and phase separates along membrane tubules

BAR domain proteins contribute to membrane deformation in diverse cellular processes. The inverted-BAR (I-BAR) protein IRSp53, for instance, is found on the inner leaflet of the tubular membrane of filopodia; however its role in the formation of these structures is incompletely understood. Here we d...

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Detalles Bibliográficos
Autores principales: Prévost, Coline, Zhao, Hongxia, Manzi, John, Lemichez, Emmanuel, Lappalainen, Pekka, Callan-Jones, Andrew, Bassereau, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634128/
https://www.ncbi.nlm.nih.gov/pubmed/26469246
http://dx.doi.org/10.1038/ncomms9529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634128/
https://www.ncbi.nlm.nih.gov/pubmed/26469246
http://dx.doi.org/10.1038/ncomms9529

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