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Structural basis for phosphatidylinositol-phosphate biosynthesis
Phosphatidylinositol is critical for intracellular signalling and anchoring of carbohydrates and proteins to outer cellular membranes. The defining step in phosphatidylinositol biosynthesis is catalysed by CDP-alcohol phosphotransferases, transmembrane enzymes that use CDP-diacylglycerol as donor su...
Autores principales: | Clarke, Oliver B., Tomasek, David, Jorge, Carla D., Dufrisne, Meagan Belcher, Kim, Minah, Banerjee, Surajit, Rajashankar, Kanagalaghatta R., Shapiro, Lawrence, Hendrickson, Wayne A., Santos, Helena, Mancia, Filippo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634129/ https://www.ncbi.nlm.nih.gov/pubmed/26510127 http://dx.doi.org/10.1038/ncomms9505 |
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