Cargando…

PTGER4 gene variant rs76523431 is a candidate risk factor for radiological joint damage in rheumatoid arthritis patients: a genetic study of six cohorts

INTRODUCTION: Prostaglandin E receptor 4 (PTGER4) is implicated in immune regulation and bone metabolism. The aim of this study was to analyze its role in radiological joint damage in rheumatoid arthritis (RA). METHODS: Six independent cohorts of patients with RA of European or North American descen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodriguez-Rodriguez, Luis, Ivorra-Cortes, Jose, Carmona, F. David, Martín, Javier, Balsa, Alejandro, van Steenbergen, Hanna W., van der Helm-van Mil, Annette H. M., González-Álvaro, Isidoro, Fernandez-Gutiérrez, Benjamín
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634155/ https://www.ncbi.nlm.nih.gov/pubmed/26538147 http://dx.doi.org/10.1186/s13075-015-0830-z

Ejemplares similares

A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis
por: van Steenbergen, Hanna W, et al.
Publicado: (2015)

Disease Activity Indices in Rheumatoid Arthritis: Comparative Performance to Detect Changes in Function, IL-6 Levels, and Radiographic Progression
por: Rodriguez-García, Sebastián C., et al.
Publicado: (2021)

Fatigue in rheumatoid arthritis; a persistent problem: a large longitudinal study
por: van Steenbergen, Hanna W, et al.
Publicado: (2015)

Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodies as an example
por: Boeters, Debbie M., et al.
Publicado: (2018)

Subclinical inflammation on MRI of hand and foot of anticitrullinated peptide antibody–negative arthralgia patients at risk for rheumatoid arthritis
por: van Steenbergen, Hanna W, et al.
Publicado: (2014)

Sequence of joint tissue inflammation during rheumatoid arthritis development
por: ten Brinck, R. M., et al.
Publicado: (2018)

Prostaglandin E2 regulates B cell proliferation through a candidate tumor suppressor, Ptger4
por: Murn, Jernej, et al.
Publicado: (2008)

Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets
por: van der Helm-van Mil, Annette HM, et al.
Publicado: (2008)

Development of clinically apparent synovitis: a longitudinal study at the joint level during progression to inflammatory arthritis
por: ten Brinck, Robin M, et al.
Publicado: (2018)

Not only synovitis but also tenosynovitis needs to be considered: why it is time to update textbook images of rheumatoid arthritis
por: Rogier, Cleo, et al.
Publicado: (2020)

Body mass index and extent of MRI-detected inflammation: opposite effects in rheumatoid arthritis versus other arthritides and asymptomatic persons
por: Mangnus, Lukas, et al.
Publicado: (2016)

The value of inquiring about functional impairments for early identification of inflammatory arthritis: a large cross-sectional derivation and validation study from the Netherlands
por: van Dijk, Bastiaan T, et al.
Publicado: (2020)

Window of opportunity in rheumatoid arthritis – definitions and supporting evidence: from old to new perspectives
por: Burgers, Leonie E, et al.
Publicado: (2019)

Is Anti–Citrullinated Protein Antibody–Positive Rheumatoid Arthritis Still a More Severe Disease Than Anti–Citrullinated Protein Antibody–Negative Rheumatoid Arthritis? A Longitudinal Cohort Study in Rheumatoid Arthritis Patients Diagnosed From 2000 Onward
por: Boer, Aleid C., et al.
Publicado: (2018)

Association of PTGER4 and PRKAA1 genetic polymorphisms with gastric cancer
por: Yu, Shuyong, et al.
Publicado: (2023)

Moderate use of alcohol is associated with lower levels of C reactive protein but not with less severe joint inflammation: a cross-sectional study in early RA and healthy volunteers
por: Mangnus, Lukas, et al.
Publicado: (2018)

Improvement of symptoms in clinically suspect arthralgia and resolution of subclinical joint inflammation: a longitudinal study in patients that did not progress to clinical arthritis
por: ten Brinck, Robin M., et al.
Publicado: (2020)

Unraveling heterogeneity within ACPA-negative rheumatoid arthritis: the subgroup of patients with a strong clinical and serological response to initiation of DMARD treatment favor disease resolution
por: Verstappen, M., et al.
Publicado: (2022)

PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11β-hydroxysteroid dehydrogenase activity by prostaglandin E(2) in human granulosa–lutein cells
por: Chandras, C, et al.
Publicado: (2007)

Identification of ACOT13 and PTGER2 as novel candidate genes of autosomal dominant polycystic kidney disease through whole exome sequencing
por: Du, Na, et al.
Publicado: (2021)

Prostaglandin E(2) Signals Through PTGER2 to Regulate Sclerostin Expression
por: Genetos, Damian C., et al.
Publicado: (2011)

Maternal and Fetal Genetic Associations of PTGER3 and PON1 with Preterm Birth
por: Ryckman, Kelli K., et al.
Publicado: (2010)

Mapping PTGERs to the Ovulatory Follicle: Regional Responses to the Ovulatory PGE2 Signal
por: Kim, Soon Ok, et al.
Publicado: (2016)

Which patients presenting with arthralgia eventually develop rheumatoid arthritis? The current state of the art
por: Boeters, Debbie M, et al.
Publicado: (2017)

MRI-detected synovitis of the small joints predicts rheumatoid arthritis development in large joint undifferentiated inflammatory arthritis
por: Sidhu, Navkiran, et al.
Publicado: (2021)

How thorough clinical observational studies on rheumatoid arthritis can have an impact on the field
por: van der Helm-van Mil, A. H. M.
Publicado: (2019)

Morning stiffness precedes the development of rheumatoid arthritis and associates with systemic and subclinical joint inflammation in arthralgia patients
por: Krijbolder, Doortje I, et al.
Publicado: (2021)

Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis
por: Mangnus, Lukas, et al.
Publicado: (2015)

Increased frequency of intermetatarsal and submetatarsal bursitis in early rheumatoid arthritis: a large case-controlled MRI study
por: Dakkak, Yousra J., et al.
Publicado: (2020)

IL2RA is associated with persistence of rheumatoid arthritis
por: van Steenbergen, H.W., et al.
Publicado: (2015)

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis
por: Shi, Jing, et al.
Publicado: (2015)

Validity of the rheumatoid arthritis MRI score applied to the forefeet using the OMERACT filter: a systematic literature review
por: Dakkak, Yousra J, et al.
Publicado: (2018)

The earlier, the better or the worse? Towards accurate management of patients with arthralgia at risk for RA
por: van der Helm-van Mil, Annette, et al.
Publicado: (2020)

During development of rheumatoid arthritis, intermetatarsal bursitis may occur before clinical joint swelling: a large imaging study in patients with clinically suspect arthralgia
por: van Dijk, Bastiaan T, et al.
Publicado: (2021)

Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis
por: van der Helm-van Mil, Annette HM, et al.
Publicado: (2005)

Is shoulder involvement in clinically suspect arthralgia an early feature of rheumatoid arthritis? A longitudinal ultrasound study
por: Rogier, Cleo, et al.
Publicado: (2020)

Maternal Protein Restriction Alters the Renal Ptger1 DNA Methylation State in SHRSP Offspring
por: Miyoshi, Moe, et al.
Publicado: (2018)

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting
por: van Heemst, Jurgen, et al.
Publicado: (2015)

An evaluation of molecular and clinical remission in rheumatoid arthritis by assessing radiographic progression
por: van der Helm-van Mil, Annette H. M., et al.
Publicado: (2013)

Improving the feasibility of MRI in clinically suspect arthralgia for prediction of rheumatoid arthritis by omitting scanning of the feet
por: Boer, Aleid C, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r0c4aq04b1uiv0jfsb2uh0o2gl