Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment

Waterfowl are primary hosts for influenza A viruses (IAVs); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow‐shouldered bats were shown to be hosts of an IAV, thereby constituting a potential novel reservoir. We show that Pteropus alecto kid...

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Detalles Bibliográficos
Autores principales: Dlugolenski, Daniel, Jones, Les, Tompkins, S. Mark, Crameri, Gary, Wang, Lin‐Fa, Tripp, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Part 1
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634287/
https://www.ncbi.nlm.nih.gov/pubmed/23710888
http://dx.doi.org/10.1111/irv.12128
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author Dlugolenski, Daniel
Jones, Les
Tompkins, S. Mark
Crameri, Gary
Wang, Lin‐Fa
Tripp, Ralph A.
author_facet Dlugolenski, Daniel
Jones, Les
Tompkins, S. Mark
Crameri, Gary
Wang, Lin‐Fa
Tripp, Ralph A.
author_sort Dlugolenski, Daniel
collection PubMed
description Waterfowl are primary hosts for influenza A viruses (IAVs); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow‐shouldered bats were shown to be hosts of an IAV, thereby constituting a potential novel reservoir. We show that Pteropus alecto kidney cells (PaKi) are susceptible to infection and sustain replication of A/WSN/33 (H1N1) and A/Vietnam/1203/04 (H5N1). Importantly, we show that co‐infection of PaKi cells results in novel reassortants.
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spelling pubmed-46342872015-12-01 Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment Dlugolenski, Daniel Jones, Les Tompkins, S. Mark Crameri, Gary Wang, Lin‐Fa Tripp, Ralph A. Influenza Other Respir Viruses Part 1 Waterfowl are primary hosts for influenza A viruses (IAVs); however, there is sporadic infection of swine and other species that pose a risk of zoonotic spread. Yellow‐shouldered bats were shown to be hosts of an IAV, thereby constituting a potential novel reservoir. We show that Pteropus alecto kidney cells (PaKi) are susceptible to infection and sustain replication of A/WSN/33 (H1N1) and A/Vietnam/1203/04 (H5N1). Importantly, we show that co‐infection of PaKi cells results in novel reassortants. John Wiley and Sons Inc. 2013-05-27 2013-11 /pmc/articles/PMC4634287/ /pubmed/23710888 http://dx.doi.org/10.1111/irv.12128 Text en © 2013 John Wiley & Sons Ltd
spellingShingle Part 1
Dlugolenski, Daniel
Jones, Les
Tompkins, S. Mark
Crameri, Gary
Wang, Lin‐Fa
Tripp, Ralph A.
Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment
title Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment
title_full Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment
title_fullStr Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment
title_full_unstemmed Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment
title_short Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment
title_sort bat cells from pteropus alecto are susceptible to influenza a virus infection and reassortment
topic Part 1
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634287/
https://www.ncbi.nlm.nih.gov/pubmed/23710888
http://dx.doi.org/10.1111/irv.12128
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