A(H1N1)pdm09 hemagglutinin D222G and D222N variants are frequently harbored by patients requiring extracorporeal membrane oxygenation and advanced respiratory assistance for severe A(H1N1)pdm09 infection

BACKGROUND: In patients with A(H1N1)pdm09 infection, severe lung involvement requiring admission to intensive care units (ICU) has been reported. Mutations at the hemagglutinin (HA) receptor binding site (RBS) have been associated with increased virulence and disease severity, representing a potenti...

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Detalles Bibliográficos
Autores principales: Ruggiero, Tina, De Rosa, Francesco, Cerutti, Francesco, Pagani, Nicole, Allice, Tiziano, Stella, Maria L., Milia, Maria G., Calcagno, Andrea, Burdino, Elisa, Gregori, Gabriella, Urbino, Rosario, Di Perri, Giovanni, Ranieri, Marco V., Ghisetti, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Part 5
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634302/
https://www.ncbi.nlm.nih.gov/pubmed/23927713
http://dx.doi.org/10.1111/irv.12146

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